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” He and Munakata think that gradual modifications in just how the DNA is saved could lead to some lack of fertility as Gals age. In that case, their investigate could pave the way in which for improved treatment method and diagnosis of fertility problems.
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Utilizing the GCRLE grant, Munakata and Namekawa will seem more intently at how oocytes are genomically primed and stored for afterwards use. They can examine the function of a chromatin remodeler in oocyte survival and fertility.
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This protein might “create and manage the chromatin state,” states Namekawa — trying to keep the spools set up and the oocytes genetically primed as being the mouse matures.
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